Publications for Zbigniew Darzynkiewicz z_darzynkiewicz@nymc.edu

Carotenuto, F., Albertini, M. C., Coletti, D., Vilmercati, A., Campanella, L., Darzynkiewicz, Z., & Teodori, L. (2016). How diet intervention via modulation of DNA damage response through microRNAs may have an effect on cancer prevention and aging, an in silico study. International Journal of Molecular Sciences, 17(5), 752. doi:10.3390/ijms17050752

Hanly, E. K., Tuli, N. Y., Suriano, R., Geliebter, J., Moscatello, A.  L., Darzynkiewicz, Z.,. . . Tiwari, R. K. (2016). Hyperactive ERK and persistent mTOR signaling characterize vemurafenib resistance in papillary thyroid cancer cells. Oncotarget, 7(8), 8676-8687. doi:10.18632/oncotarget.6779

Darzynkiewicz, Z. (2015). Rapid and simple detection of gero-suppressive agents. Oncotarget, 6(27), 23050-23051. doi:10.18632/oncotarget.5455

Darzynkiewicz, Z. +., Zhao, H. +., Zhang, S. +., Lee, M. Y. +., Lee, E. Y. +., & Zhang, Z. +. (2015). Initiation and termination of DNA replication during S phase in relation to cyclins D1, E and A, p21WAF1, Cdt1 and the p12 subunit of DNA polymerase delta revealed in individual cells by cytometry. Oncotarget, 6(14), 11735-11750. doi:10.18632/oncotarget.4149

Hanly, E. K., Bednarczyk, R. B., Moscatello, A. L., Halicka, H. D., Geliebter, J., Darzynkiewicz, Z., . . . Tiwari, R. K. (2015). mTOR inhibitors sensitize thyroid cancer cells to cytotoxic effect of vemurafenib. Oncotarget, 6(37), 39702-39713. doi:10.18632/oncotarget.4052

Hanly, E. K., Darzynkiewicz, Z., & Tiwari, R. K. (2015). Biguanides and targeted anti-cancer treatments. Genes & Cancer, 6(3-4), 82-83. doi:10.18632/genesandcancer.59

Hanly, E. K., Tuli, N. Y., Suriano, R., Geliebter, J., Moscatello, A. L., Darzynkiewicz, Z.,. . . Tiwari, R. K. (2015). Hyperactive ERK and persistent mTOR signaling characterize vemurafenib resistance in papillary thyroid cancer cells. Oncotarget, 7(8), 8676-8687. doi:10.18632/oncotarget.6779

Darzynkiewicz, Z., Zhao, H., Halicka, H. D., Li, J., Lee, Y. S., Hsieh, T. C., & Wu, J. M. (2014). In search of antiaging modalities: Evaluation of mTOR- and ROS/DNA damage-signaling by cytometry. Cytometry. Part A, 85(5), 386-399. doi:10.1002/cyto.a.22452

Hanly, E. K., Darzynkiewicz, Z., Zhao, H., Suriano, R., Shin, E. J., Geliebter, J., . . . Tiwari, R. K. (2014). Disruption of mutated BRAF signaling modulates thyroid cancer phenotype. BMC Research Notes, 7, 187. doi:10.1186/1756-0500-7-187

Hao, S., Bellner, L., Zhao, H., Ratliff, B. B., Darzynkiewicz, Z., Vio, C. P., & Ferreri, N. R. (2014). NFAT5 is protective against ischemic acute kidney injury. Hypertension, 63(3), e46-e52.  doi:10.1161/HYPERTENSIONAHA.113.02476

Lee, M. Y., Zhang, S., Lin, S. H., Wang, X., Darzynkiewicz, Z., Zhang, Z., & Lee, E. Y. (2014). The tail that wags the dog: p12, the smallest subunit of DNA polymerase δ is degraded by ubiquitin ligases in response to DNA damage and during cell cycle progression. Cell Cycle, 13(1), 23-31. doi:10.4161/cc.27407

Li, B., Zhao, H., Rybak, P., Dobrucki, J. W., Darzynkiewicz, Z., & Kimmel, M. (2014). Different rates of DNA replication at early versus late S-phase sections: multiscale modeling of stochastic events related to DNA content/EdU (5-ethynyl-2'deoxyuridine) incorporation distributions. Cytometry. Part A, 85(9), 785-797. doi:10.1002/cyto.a.22484

MacEwan, M. E., Zhao, H., Iacob, C., Moscatello, A., Shin, E., Tiwari, R., Darzynkiewicz, Z.,. . . Geliebter, J. (2014). Androgen decreases proliferation of thyroid cancer cells. Cancer Research, 74(19 Suppl.), 2122. doi:10.1158/1538-7445.AM2014-2122

Smolewski, P., Witkowska, M., Zwolinska, M., Cebula-Obrzut, B., Majchrzak, A., Jeske, A., . . . Darzynkiewicz, Z. (2014). Cytotoxic activity of the amphibian ribonucleases onconase and r-amphinase on tumor cells from B cell lymphoproliferative disorders. International Journal of Oncology, 45(1), 419-425. doi:10.3892/ijo.2014.2405

Stobezki, R., Titus, S., Halicka, D., Darzynkiewicz, Z., & Oktay, K. (2014). Declining DNA double strand break repair results in male reproductive aging. Fertility and Sterility, 102(3 Suppl.), e110.

Zhao, H., & Darzynkiewicz, Z. (2014). Attenuation of replication stress-induced premature cellular senescence to assess anti-aging modalities. Current Protocols in Cytometry, 69, 9.47.1-9.47.10. doi:10.1002/0471142956.cy0947s69

Zhao, H., Zhang, S., Xu, D., Lee, M. Y., Zhang, Z., Lee, E. Y., & Darzynkiewicz, Z. (2014). Expression of the p12 subunit of human DNA polymerase δ (Pol δ), CDK inhibitor p21WAF1, Cdt1, cyclin A, PCNA and Ki-67 in relation to DNA replication in individual cells. Cell Cycle, 13(22), 3529-3540. doi:10.4161/15384101.2014.958910

Akagi, J., Kordon, M., Zhao, H., Matuszek, A., Dobrucki, J., Errington, R., . . . Darzynkiewicz, Z. (2013). Real-time cell viability assays using a new anthracycline derivative DRAQ7®. Cytometry Part A, 83A(2), 227-234. doi:10.1002/cyto.a.22228

Bernas, T., Berniak, K., Rybak, P., Zarebski, M., Zhao, H., Darzynkiewicz, Z., & Dobrucki, J. W. (2013). Analysis of spatial correlations between patterns of DNA damage response and DNA replication in nuclei of cells subjected to replication stress or oxidative damage. Cytometry Part A, 83(10), 925-932. doi:10.1002/cyto.a.22325

Berniak, K., Rybak, P., Bernas, T., Zarebski, M., Biela, E., Zhao, H., . . . Darzynkiewicz, Z. (2013). Relationship between DNA damage response, initiated by camptothecin or oxidative stress, and DNA replication, analyzed by quantitative 3D image analysis. Cytometry Part A, 83(10), 913-924. doi:10.1002/cyto.a.22327

Biela, E., Galas, J., Lee, B., Johnson, G. L., Darzynkiewicz, Z., & Dobrucki, J. W. (2013). Col-F, a fluorescent probe for ex vivo confocal imaging of collagen and elastin in animal tissues. Cytometry Part A, 83A(6), 533-539. doi:10.1002/cyto.a.22264

Darzynkiewicz, Z. (2013). Perturbation of nucleotide metabolism - the driving force of oncogene-induced senescence. Oncotarget, 4(5), 649-650. PMCID: PMC3742826

Majchrzak, A., Witkowska, M., Medra, A., Zwolinska, M., Bogusz, J., Cebula-Obrzut, B., . . . Darzynkiewicz, Z. (2013). In vitro cytotoxicity of ranpirnase (onconase) in combination with components of R-CHOP regimen against diffuse large B cell lymphoma (DLBCL) cell line. Postepy Higieny i Medycyny Doswiadczalnej (Online) [Progression of Hygiene and Experimental Medicine], 67, 1166-1172. doi:10.5604/17322693.1078386

Pozarowski, P., Holden, E., & Darzynkiewicz, Z. (2013). Laser scanning cytometry: Principles and applications-an update. Methods in Molecular Biology, 931, 187-212. doi:10.1007/978-1-62703-056-4_11

Tarnok, A., & Darzynkiewicz, Z. (2013). New insights into cell cycle and DNA damage response machineries through high-resolution AMICO quantitative imaging cytometry. Cell Proliferation, 46(5), 497-500. doi:10.1111/cpr.12050