Publications for David J. Evans david.evans@tu.edu

Li, J., Metruccio, M. M. E., Evans, D. J., & Fleiszig, S. M. J. (2017). Mucosal fluid glycoprotein DMBT1 suppresses twitching motility and virulence of the opportunistic pathogen Pseudomonas aeruginosa. PLoS ONE, 13(5) [Article e1006392]. This material can be found here.

Wu, Y. T., Tam, C., Zhu, L. S., Evans, D. J., & Fleiszig, S. M. J. (2017). Human tear fluid reduces culturability of contact lens-associated Pseudomonas aeruginosa biofilms but induces expression of the virulence-associated type III secretion system. Ocular Surface, 15(1), 88-96. doi:10.1016/j.jtos.2016.09.001

Metruccio, M. M. E., Evans, D. J., Gabriel, M. M., Kadurugamuwa, J. L., & Fleiszig, S. M. J. (2016). Pseudomonas aeruginosa outer membrane vesicles triggered by human mucosal fluid and lysozyme can prime host tissue surfaces for bacterial adhesion. Frontiers in Microbiology, 7 [Article 00871]. doi:10.3389/fmicb.2016.00871

Sorenson, A. L., Sorenson, R. L., & Evans, D. J. (2016). Toxic anterior segment syndrome caused by autoclave reservoir wall biofilms and their residual toxins. Journal of Cataract & Refractive Surgery, 42(11), 1602-1614. doi:10.1016/j.jcrs.2016.08.030

Jolly, A. L., Takawira, D., Oke, O. O., Whiteside, S. A., Chang, S. W., Wen, E. R., . . . Evans, D. J. (2015). Pseudomonas aeruginosa-induced bleb-niche formation in epithelial cells is independent of actinomyosin contraction and enhanced by loss of cystic fibrosis transmembrane-conductance regulator osmoregulatory function. mBio, 6(2) [Article e02533-14]. doi:10.1128/mBio.02533-14

Sullivan, A. B., Tam, K. P., Metruccio, M. M., Evans, D. J., & Fleiszig, S. M. (2015). The importance of the Pseudomonas aeruginosa type III secretion system in epithelium traversal depends upon conditions of host susceptibility. Infection and Immunity, 83(4), 1629-1640. doi:10.1128/IAI.02329-14

Wu, Y. T., Zhu, L. S., Tam, K. P. C., Evans, D. J., & Fleiszig, S. M. J. (2015). Pseudomonas aeruginosa survival at posterior contact lens surfaces after daily wear. Optometry & Vision Science, 92(6), 659-664. doi:10.1097/OPX.0000000000000597

Borkar, D. S., Acharya, N. R., Leong, C., Lalitha, P., Srinivasan, M., Oldenburg, C. E., . . . Evans, D. J. (2014). Cytotoxic clinical isolates of Pseudomonas aeruginosa identified during the Steroids for Corneal Ulcers Trial show elevated resistance to fluoroquinolones. BMC Ophthalmology, 14 [Article 54]. doi:10.1186/1471-2415-14-54

Evans, D. J., & Fleiszig, S. M. J. (2013). Microbial keratitis: Could contact lens material affect disease pathogenesis? Eye and Contact Lens, 39(1), 73-78.  doi:10.1097/ICL.0b013e31827c5b73

Evans, D. J., & Fleiszig, S. M. J. (2013). Why does the healthy cornea resist pseudomonas aeruginosa infection? American Journal of Ophthalmology, 155(6), 961-970.e2.  doi:10.1016/j.ajo.2013.03.001

Heimer, S. R., Evans, D. J., Mun, J. J., Stern, M. E., & Fleiszig, S. M. (2013). Surfactant protein D contributes to ocular defense against pseudomonas aeruginosa in a murine model of dry eye disease. PLoS One, 8(6) [Article e65797].  doi:10.1371/journal.pone.0065797

Heimer, S. R., Evans, D. J., Stern, M. E., Barbieri, J. T., Yahr, T., & Fleiszig, S. M. J. (2013). Pseudomonas aeruginosa utilizes the type III secreted toxin ExoS to avoid acidified compartments within epithelial cells. PLoS One, 8(9) [Article e73111].  doi:10.1371/journal.pone.0073111

Mun, J., Tam, C., Chan, G., Kim, J. H., Evans, D. J., & Fleiszig, S. M. J.(2013). MicroRNA-762 is upregulated in human corneal epithelial cells in response to tear fluid and pseudomonas aeruginosa antigens and negatively regulates the expression of host defense genes encoding RNase7 and ST2. PLoS One, 8(2) [Article e57850]. doi:10.1371/journal.pone.0057850

Hritonenko, V., Evans, D. J., & Fleiszig, S. M. J. (2012). Translocon-independent intracellular replication by Pseudomonas aeruginosa requires the ADP-ribosylation domain of ExoS. Microbes and Infection, 14(15), 1366-1373. doi:10.1016/j.micinf.2012.08.007

Ramirez, J. C., Fleiszig, S. M. J., Sullivan, A. B., Tam, C., Borazjani, R., & Evans, D. J. (2012). Traversal of multilayered corneal epithelia by cytotoxic Pseudomonas aeruginosa requires the phospholipase domain of exoU. Investigative Ophthalmology and Visual Science, 53(1), 448-453. PMCID: PMC3292376

Tam, C., Mun, J. J., Evans, D. J., & Fleiszig, S. M. J. (2012). Cytokeratins mediate epithelial innate defense through their antimicrobial properties. Journal of Clinical Investigation, 122(10), 3665-3677.  doi:10.1172/JCI64416

Alarcon, I., Tam, C., Mun, J., LeDue, J., Evans, D. J., & Fleiszig, S. M. J. (2011). Factors impacting corneal epithelial barrier function against Pseudomonas aeruginosa traversal. Investigative Ophthalmology and Visual Science, 52(3), 1368-1377. doi:10.1167/iovs.10-6125

Hritonenko, V., Mun, J. J., Tam, C., Simon, N. C., Barbieri, J. T., Evans, D. J., & Fleiszig, S. M. J. (2011). Adenylate cyclase activity of Pseudomonas aeruginosa ExoY can mediate bleb-niche formation in epithelial cells and contributes to virulence. Microbial Pathogenesis, 51(5), 305-312.

Mun, J. J., Tam, C., Evans, D. J., & Fleiszig, S. M. J. (2011). Modulation of epithelial immunity by mucosal fluid. Scientific Reports, 1 [Article 8]. doi:10.1038/srep00008

Tam, C., LeDue, J., Mun, J. J., Herzmark, P., Robey, E. A., Evans, D. J., & Fleiszig, S. M. J. (2011). 3D quantitative imaging of unprocessed live tissue reveals epithelial defense against bacterial adhesion and subsequent traversal requires MyD88. PLoS One, 6(8), e24008. doi:10.1371/journal.pone.0024008

Tran, V. B., Fleiszig, S. M. J., Evans, D. J., & Radke, C. J. (2011). Dynamics of flagellum- and pilus-mediated association of Pseudomonas aeruginosa with contact lens surfaces. Applied Environmental Microbiology, 77(11), 3644-3652.

Tran, V. B., Sung, Y. S., Fleiszig, S. M. J., Evans, D. J., & Radke, C. J. (2011). Dynamics of Pseudomonas aeruginosa association with anionic hydrogel surfaces in the presence of aqueous divalent-cation salts. Journal of Colloid and Interface Science, 362(1), 58-66.

Angus, A. A., Evans, D. J., Barbieri, J. T., & Fleiszig, S. M. J. (2010). The ADP-ribosylation domain of Pseudomonas aeruginosa ExoS is required for membrane bleb niche formation and bacterial survival within epithelial cells. Infection and Immunity, 78, 4500-4510. doi:10.1128/IAI.00417-10

Augustin, D. K., Heimer, S. R., Tam, C., Li, W., LeDue, J., Evans, D. J., Fleiszig, S. M. J. (2010). Role of defensins in corneal epithelial barrier function against Pseudomonas aeruginosa traversal. Infection and Immunity, 79(2), 595-605. doi:10.1128/IAI.00854-10

Fleiszig, S. M. J., & Evans, D. J. (2010). Pathogenesis of contact lens-associated microbial keratitis. Optometry and Vision Science, 87(4), 225-232. This material can be found here.