Publications for Sachin Gupte s_gupte@nymc.edu

Chettimada, S., Joshi, S. R., Dhagia, V., Aiezza II, A., Lincoln, T. M., Gupte, R., . . . Gupte, S. A. (2016). Vascular smooth muscle cell contractile protein expression is increased through PKG-dependent and -independent pathways by G6PD inhibition and deficiency. American Journal of Physiology.Heart and Circulatory Physiology, 311(4), H904-H912. doi:10.1152/ajpheart.00335.2016

Joshi, S. R., Dhagia, V., Gairhe, S., Edwards, J. G., McMurtry, I. F., & Gupte, S. A. (2016). MicroRNA-140 is elevated and mitofusin-1 is downregulated in the right ventricle of the Sugen5416/hypoxia/normoxia model of pulmonary arterial hypertension. American Journal of Physiology. Heart and Circulatory Physiology, 311(3), H689-H698. doi:10.1152/ajpheart.00264.2016

Joshi, S. R., Lakhkar, A., Dhagia, V., Zias, A. L., Jiang, H., Schwartzman, M. L.,. . . Gupte, S. A. (2016). Cyp2c44 gene disruption exacerbated pulmonary hypertension and heart failure in female but not male mice. Pulmonary Circulation, 6(3), 360-368. doi:10.1086/688060

Kizub, I. V., Lakhkar, A., Dhagia, V., Joshi, S. R., Wolin, M. S., Schwartzman,  M. L.,. . . Gupte, S. A. (2016). Involvement of gap junctions between smooth muscle cells in sustained hypoxic pulmonary vasoconstriction development: A potential role for 15-HETE and 20-HETE. American Journal of Physiology. Lung Cellular and Molecular Physiology, 310(8), L772-L783. doi:10.1152/ajplung.00377.2015

Lakhkar, A., Dhagia, V., Joshi, S. R., Sun, D., Wolin, M. S., Schwartzman, M. L., . . . Gupte, S. A. (2016). 20-HETE-induced mitochondrial superoxide production and inflammatory phenotype in vascular smooth muscle is prevented by glucose-6-phosphate dehydrogenase inhibition. American Journal of Physiology. Heart and Circulatory Physiology, 310(9), H1107-H1117. doi:10.1152/ajpheart.00961.2015

Ochi, R., Dhagia, V., Patel, D., Wolin, M. S., & Gupte, S. A. (2016). L-type Ca2+ current increase by rotenone, stimulant of mitochondrial superoxide release, in A7r5 arterial smooth muscle cells. effect of dithiothreitol, hydrogen peroxide, tempol and staurosporine. FASEB Journal, 30(Suppl 1), 1224.15. 

Ochi, R., Dhagia, V., Patel, D., Wolin, M. S., & Gupte, S. A. (2016). Rotenone, stimulant of superoxide release from mitochondrial complex I, transiently augments L-type calcium current in A7r5 arterial smooth muscle cells. Biophysical Journal, 110(3), 441A. doi:10.1016/j.bpj.2015.11.2375

Chettimada, S., Gupte, R., Rawat, D., Gebb, S. A., McMurtry, I. F., & Gupte, S. A. (2015). Hypoxia-induced glucose-6-phosphate dehydrogenase overexpression and -activation in pulmonary artery smooth muscle cells: Implication in pulmonary hypertension. American Journal of Physiology - Lung Cellular and Molecular Physiology, 308(3), L287-L300. doi:10.1152/ajplung.00229.2014

Chettimada, S., Ata, H., Rawat, D. K., Gulati, S., Kahn, A. G., Edwards, J. G., & Gupte, S. A. (2014). Contractile protein expression is upregulated by reactive oxygen species in aorta of Goto-Kakizaki rat. American Journal of Physiology. Heart and Circulatory Physiology, 306(2), H214-224. doi:10.1152/ajpheart.00310.2013

Chettimada, S., Joshi, S. R., Al Zoubi, A., Gebb, S. A., McMurtry, I. F., Gupte, R. S., & Gupte, S. A. (2014). Glucose-6-phosphate dehydrogenase plays a critical role in hypoxia-induced CD133+ progenitor cells self-renewal. American Journal of Physiology. Lung Cellular and Molecular Physiology, 307(7), L545-556. doi:ajplung.00303.2013

Gupte, S., Strother, J., Hodge, J., Gupte, R., & Gulati, S. (2014). Effect of thermal injury on TRPV4 and c-Kit+ stem cells in skin. Journal of Burn Care and Research, 35(Suppl. 1), S207.

Joshi, S., Alloosh, M., & Gupte, S. (2014). Glucose-6-phosphate dehydrogenase is involved in regulation of arterial smooth muscle phenotype in metabolic syndrome. FASEB Journal, 28(1 Suppl.), 1076.5.

Lakhkar, A., Joshi, S., & Gupte, S. (2014). Regulation of cGMP by glucose-6-phosphate dehydrogenase through PDE5 In coronary artery. FASEB Journal, 28(1 Suppl), 849.2.

Ochi, R., Chettimada, S., & Gupte, S. A. (2014). Poly(ethylene glycol)-cholesterol inhibits L-type Ca2+ channel currents and augments voltage-dependent inactivation in A7r5 cells. PLoS One, 9(9), e107049. doi:10.1371/journal.pone.0107049

Ochi, R., Chettimada, S., Wolin, M., & Gupte, S. (2014). L-type Ca2+ channel current is controlled by ROS regulated by glucose-6-phosphate dehydrogenase and mitochondrial respiratory chain complex i. FASEB Journal, 28(1 Suppl.), 698.2.

Rawat, D. K., Alzoubi, A., Gupte, R., Chettimada, S., Watanabe, M., Kahn, A. G., . . . & Gupte, S. A. (2014). Increased reactive oxygen species, metabolic maladaptation, and autophagy contribute to pulmonary arterial hypertension-induced ventricular hypertrophy and diastolic heart failure. Hypertension, 64(6), 1266-1274. doi:10.1161/HYPERTENSIONAHA.114.03261

Vimercati, C., Qanud, K., Mitacchione, G., Sosnowska, D., Ungvari, Z., Hintze, T. H., . . . Gupte, S. A. (2014). Beneficial effects of acute inhibition of the oxidative pentose phosphate pathway in the failing heart. American Journal of Physiology. Heart and Circulatory Physiology, 306(5), H709-H717. doi:10.1152/ajpheart.00783.2013