Publications for John Thomas Pinto john_pinto@nymc.edu

Cooper, A. J., Shurubor, Y. I., Dorai, T., Pinto, J. T., Isakova, E. P., Deryabina, Y. I., . . . Krasnikov, B. F. (2016). Omega-amidase: An underappreciated, but important enzyme in L-glutamine and L-asparagine metabolism; relevance to sulfur and nitrogen metabolism, tumor biology and hyperammonemic diseases. Amino Acids, 48(1), 1-20. doi:10.1007/s00726-015-2061-7

Dorai, T., Pinto, J. T., & Cooper, A. J. (2016). Sweetening of glutamine metabolism in cancer cells by Rho GTPases through convergence of multiple oncogenic signaling pathways. Translational Cancer Research, 5(S2), S349-S356. doi:10.21037/tcr.2016.07.43

Jeitner, T. M., Kristoferson, E., Azcona, J. A., Pinto, J. T., Stalnecker, C., Erickson, J. W., . . . Cooper, A. J. L. (2016). Fluorination at the 4 position alters the substrate behavior of l-glutamine and l-glutamate: Implications for positron emission tomography of neoplasias. Journal of Fluorine Chemistry, 192(Part A), 58-67. doi:10.1016/j.jfluchem.2016.10.008

Cooper, A. J., Shurubor, Y. I., Dorai, T., Pinto, J. T., Isakova, E. P., Deryabina, Y. I., . . . Krasnikov, B. F. (2015). Erratum to: Omega-amidase: An underappreciated, but important enzyme in L-glutamine and L-asparagine metabolism; relevance to sulfur and nitrogen metabolism, tumor biology and hyperammonemic diseases. Amino Acids, 47(12), 2671-2672. doi:10.1007/s00726-015-2115-x

Csiszar, A., Csiszar, A., Pinto, J. T., Gautam, T., Kleusch, C., Hoffmann, B., . . . Ungvari, Z. (2015). Resveratrol encapsulated in novel fusogenic liposomes activates Nrf2 and attenuates oxidative stress in cerebromicrovascular endothelial cells from aged rats. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 70(3), 303-313. doi:10.1093/gerona/glu029

Huang, A., Pinto, J. T., Froogh, G., Kandhi, S., Wolin, M. S., Hintze, T. H., . . . Sun, D. (2015). Role of homocysteinylation of ACE in endothelial dysfunction of arteries. American Journal of Physiology. Heart and Circulatory Physiology, 308(2), H92-H100. doi:10.1152/ajpheart.00577.2014

Sleiman, S. F., Olson, D. E., Bourassa, M. W., Karuppagounder, S. S., Zhang, Y. L., Gale, J., . . . Pinto, J. T. (2015). Correction: Sleiman et al., Hydroxamic acid-based histone deacetylase (HDAC) inhibitors can mediate neuroprotection independent of hdac inhibition. Journal of Neuroscience, 35(1), 438. doi:10.1523/JNEUROSCI.4746-14.2015

Aquilato, A., Lopez, V., Doonan, B., Hsieh, T. C., Pinto, J. T., Wu, E., & Wu, J. M. (2014). BRAF mutation in melanoma and dietary polyphenols as adjunctive treatment strategy. In R. R. Watson, V. R. Preedy, & S. Zibadi (Eds.), Polyphenols in human health and disease (pp. 1353-1365). Amsterdam, Netherlands: Elsevier/Academic Press.

Kang, Y., Nian, H., Rajendran, P., Kim, E., Dashwood, W. M., Pinto, J. T., . . . Dashwood, R. H. (2014). HDAC8 and STAT3 repress BMF gene activity in colon cancer cells. Cell Death & Disease, 5, e1476. doi:10.1038/cddis.2014.422

Pinto, J. T. , & Cooper, A. J. (2014). From cholesterogenesis to steroidogenesis: Role of riboflavin and flavoenzymes in the biosynthesis of vitamin D. Advances in Nutrition, 5(2), 144-163. doi:10.3945/an.113.00518

Pinto, J. T., & Rivlin, R. S. (2014). Ribovlavin (Vitamin B2). In Zempleni, J., Suttie, J. W., Gregory III, J. F. & Stover, P. J. (Eds.), Handbook of vitamins, 5th ed., (pp. 191-265). Boca Raton, FL: CRC Press.

Pinto, J. T., Krasnikov, B. F., Alcutt, S., Jones, M. E., Dorai, T., Villar, M. T., . . . Cooper, A. J. (2014). Kynurenine aminotransferase III and glutamine transaminase L are identical enzymes that have cysteine S-conjugate beta-lyase activity and can transaminate L-selenomethionine. The Journal of Biological Chemistry, 289(45), 30950-30961. doi:10.1074/jbc.M114.591461

Sinha, I., Allen, J. E., Pinto, J. T., & Sinha, R. (2014). Methylseleninic acid elevates REDD1 and inhibits prostate cancer cell growth despite AKT activation and mTOR dysregulation in hypoxia. Cancer Medicine, 3(2), 252-264. doi:10.1002/cam4.198

Sleiman, S. F., Olson, D. E., Bourassa, M. W., Karuppagounder, S. S., Zhang, Y. L., & Pinto, J. T. (2014). Hydroxamic acid-based histone deacetylase (HDAC) inhibitors can mediate neuroprotection independent of HDAC inhibition. The Journal of Neuroscience, 34(43), 14328-14337. doi:10.1523/JNEUROSCI.1010-14.2014

Vauzour, D., Pinto, J. T., Cooper, A. J., & Spencer, J. P. (2014). The neurotoxicity of 5-S-cysteinyldopamine is mediated by the early activation of ERK1/2 followed by the subsequent activation of ASK1/JNK1/2 pro-apoptotic signalling. The Biochemical Journal, 463(1), 41-52. doi:10.1042/BJ20131519