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Publications for Guangyan Zhou guangyan.zhou@tu.edu

College of Osteopathic Medicine (TUC)

  • Chu, S., Zhou, G., & Gochin, M. (2017). Evaluation of ligand-based NMR screening methods to characterize small molecule binding to HIV-1 glycoprotein-41. Organic & Biomolecular Chemistry, 15(24), 5210-5219. This material can be found here.

  • Liu, S., Louie, M. C., Rajagopalan, V., Zhou, G., Ponce, E., Nguyen, T., & Green, L. (2015). Synthesis and evaluation of the diarylthiourea analogs as novel anti-cancer agents. Bioorganic & Medicinal Chemistry Letters, 25(6), 1301-1305. doi:10.1016/j.bmcl.2015.01.042

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  • Ananthan, S., Saini, S. K., Zhou, G., Hobrath, J. V., Padmalayam, I., Zhai, L., . . . Luedtke, R. R. (2014). Design, synthesis, and structure–activity relationship studies of a series of [4-(4-carboxamidobutyl)]-1-arylpiperazines: Insights into structural features contributing to dopamine D3 versus D2 receptor subtype selectivity. Journal of Medicinal Chemistry, 57(16), 7042-7060. doi:10.1021/jm500801r

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  • Zhou, G., Sofiyev, V., Kaur, H., Snyder, B. A., Mankowski, M. K., Hogan, P. A., . . . Gochin, M. (2014). Structure-activity relationship studies of indole-based compounds as small molecule HIV-1 fusion inhibitors targeting glycoprotein 41. Journal of Medicinal Chemistry, 57(12), 5270–5281. doi:10.1021/jm500344y

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  • Zhou, G., & Chu, S. (2013). Discovery of small molecule fusion inhibitors targeting HIV-1 gp41. Current Pharmaceutical Design, 19(10), 1818-1826.  doi:10.2174/1381612811319100006

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  • Gochin, M., & Zhou, G. (2011). Amphipathic properties of HIV-1 gp41 fusion inhibitors. Current Topics in Medicinal Chemistry, 11(24), 3022-3032. This material can be found here.

  • Gochin, M., & Zhou, G. (2011). U.S. Patent No. 8,455,516. Washington, DC: U.S. Patent and Trademark Office.

  • Gochin, M., Zhou, G., & Phillips, A. H. (2011). Paramagnetic relaxation assisted docking of a small indole compound in the HIV-1 gp41 hydrophobic pocket. ACS Chemical Biology, 6(3), 267-274. This material can be found here.

  • Zhou, G., Liu, X., Su, D., Li, L., Xiao, M., & Wang, P. G. (2011). Large scale enzymatic synthesis of oligosaccharides and a novel purification process. Bioorganic & Medicinal Chemistry Letters, 21(1), 311-314.

  • Zhou, G., Wu, D., Snyder, B., Ptak, R. G., Kaur, H., & Gochin, M. (2011). Development of indole compounds as small molecule fusion inhibitors targeting HIV-1 Glycoprotein-41. Journal of Medicinal Chemistry, 54(20), 7220–7231.